Serum CYFRA 21-1 but not Vimentin is Associated with Poor Prognosis in Advanced Lung Cancer Patients
نویسندگان
چکیده
منابع مشابه
CYFRA 21-1 serum analysis in patients with esophageal cancer.
This study was conducted to determine a potential use of CYFRA 21-1 in patients suffering from carcinoma of the esophagus. CYFRA 21-1 serum concentrations of 50 patients with histologically proven malignant lesion of the esophagus were compared with 50 healthy persons, 50 patients with benign esophageal disease, and 50 patients with benign lung disease. Additional analysis of serum carcinoembry...
متن کاملCYFRA 21-1 is an early predictor of chemotherapeutic effectiveness in advanced nonsmall cell lung cancer
Serum cytokeratin 19 fragment (CYFRA21-1) has been found to be a useful prognostic marker in lung cancer. Previous studies have revealed that change in CYFRA21-1 synchronously predicted therapeutic effectiveness in advanced nonsmall cell lung cancer (NSCLC) after the second cycle of chemotherapy. The objective of this study was to investigate the early predictive value of percentage change in s...
متن کاملPrognostic value of combination of Cyfra 21-1, CEA and NSE in patients with advanced non-small cell lung cancer.
OBJECTIVE To assess the value of Cyfra 21-1, carcino-embryonic antigen (CEA) and neuron-specific enolase (NSE) combined, all three together as prognostic factors in advanced stage non-small cell lung cancer (NSCLC) patients. PATIENTS AND METHODS Serum samples from untreated NSCLC patients were prospectively collected. All assays were performed using commercial kits blind to clinical informati...
متن کاملCystic brain metastasis is associated with poor prognosis in patients with advanced breast cancer
PURPOSE Brain metastasis (BM) with a cystic component from breast cancer is rare and largely uncharacterized. The purpose of this study was to identify the characteristics of cystic BM in a large cohort of breast cancer patients. RESULTS A total of 35 eligible patients with cystic BM and 255 patients with solid BM were analyzed. Three factors were significantly associated with an increased pr...
متن کاملSerum CYFRA 21-1 in advanced stage non-small cell lung cancer: an early measure of response.
OBJECTIVES Our objective was to test the prognostic importance of both the pretreatment level and change in serum CYFRA 21-1 after one cycle of chemotherapy in patients with advanced non-small cell lung cancer (NSCLC) and to compare these two CYFRA variables to routine clinical stage and response as measured by imaging. PATIENTS AND METHODS Our patients consisted of 58 with advanced NSCLC who...
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ژورنال
عنوان ژورنال: The Open Respiratory Medicine Journal
سال: 2019
ISSN: 1874-3064
DOI: 10.2174/1874306401913010031